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ARNT 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00000405-T01
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-ARNT full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 86.9
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-ARNT antibody (H00000405-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00000405-T01
    ARNT transfected lysate.
    Western Blot
    QC Testing of H00000405-T01
    Lane 1: ARNT transfected lysate ( 86.9 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 405
  • Protein Accession#:
  • -
  • Gene Name:
  • ARNT
  • Gene Alias:
  • HIF-1beta,HIF1B,HIF1BETA,TANGO,bHLHe2
  • Gene Description:
  • aryl hydrocarbon receptor nuclear translocator
  • Gene Summary:
  • The aryl hydrocarbon (Ah) receptor is involved in the induction of several enzymes that participate in xenobiotic metabolism. The ligand-free, cytosolic form of the Ah receptor is complexed to heat shock protein 90. Binding of ligand, which includes dioxin and polycyclic aromatic hydrocarbons, results in translocation of the ligand-binding subunit only to the nucleus. Induction of enzymes involved in xenobiotic metabolism occurs through binding of the ligand-bound Ah receptor to xenobiotic responsive elements in the promoters of genes for these enzymes. This gene encodes a protein that forms a complex with the ligand-bound Ah receptor, and is required for receptor function. The encoded protein has also been identified as the beta subunit of a heterodimeric transcription factor, hypoxia-inducible factor 1 (HIF1). A t(1;12)(q21;p13) translocation, which results in a TEL-ARNT fusion protein, is associated with acute myeloblastic leukemia. Three alternatively spliced variants encoding different isoforms have been described for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000032943,dioxin receptor, nuclear translocator,hypoxia-inducible factor 1, beta subunit
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