PHOX2A 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
- More Functions
SDS-PAGE Gel
PHOX2A transfected lysate.
Western Blot
Lane 1: PHOX2A transfected lysate ( 29.7 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-PHOX2A full-length
Host
Human
Theoretical MW (kDa)
29.7
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-PHOX2A antibody (H00000401-B01) by Western Blots.
SDS-PAGE Gel
PHOX2A transfected lysate.
Western Blot
Lane 1: PHOX2A transfected lysate ( 29.7 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — PHOX2A
Entrez GeneID
401GeneBank Accession#
NM_005169.2Protein Accession#
-Gene Name
PHOX2A
Gene Alias
ARIX, CFEOM2, FEOM2, MGC52227, NCAM2, PMX2A
Gene Description
paired-like homeobox 2a
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. [provided by RefSeq
Other Designations
aristaless homeobox homolog|arix homeodomain protein
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Interactome
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Disease
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