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PHOX2A Pre-design Chimera RNAi

  • Catalog # : H00000401-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens paired-like (aristaless) homeobox 2a (PHOX2A), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_005169
  • Target Region:
  • Coding sequence
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 401
  • Gene Name:
  • PHOX2A
  • Gene Alias:
  • Gene Description:
  • paired-like homeobox 2a
  • Gene Summary:
  • The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. [provided by RefSeq
  • Other Designations:
  • aristaless homeobox homolog,arix homeodomain protein
  • Related Disease
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