RND3 purified MaxPab mouse polyclonal antibody (B02P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of RND3 expression in transfected 293T cell line (H00000390-T02) by RND3 MaxPab polyclonal antibody.
Lane 1: RND3 transfected lysate(26.84 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human RND3 protein.
Immunogen
RND3 (NP_005159.1, 1 a.a. ~ 244 a.a) full-length human protein.
Sequence
MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKSCTVM
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of RND3 expression in transfected 293T cell line (H00000390-T02) by RND3 MaxPab polyclonal antibody.
Lane 1: RND3 transfected lysate(26.84 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — RND3
Entrez GeneID
390GeneBank Accession#
NM_005168Protein Accession#
NP_005159.1Gene Name
RND3
Gene Alias
ARHE, Rho8, RhoE, memB
Gene Description
Rho family GTPase 3
Omim ID
602924Gene Ontology
HyperlinkGene Summary
Members of the Rho family of Ras-related GTPases, such as ARHE, regulate the organization of the actin cytoskeleton in response to extracellular growth factors. Like Ras (MIM 190020), Rho family members appear to cycle between an inactive GDP-bound form and an active GTP-bound form. Three major regulators of Rho activity have been identified: RhoGDIs, which interact with the GDP-bound Rho proteins to keep them in a resting complex (see MIM 601925); GEFs, which promote GDP/GTP exchange leading to activation of Rho proteins (see MIM 601855); and GAPs, which stimulate GTP hydrolysis and return the activated Rho protein to its inactive form (see MIM 602680) (Nobes et al., 1998 [PubMed 9531558]).[supplied by OMIM
Other Designations
OTTHUMP00000162685|ras homolog gene family, member E|small GTP binding protein Rho8
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