ARG2 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-ARG2 full-length
Host
Human
Theoretical MW (kDa)
38.6
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-ARG2 antibody (H00000384-B01) by Western Blots.
SDS-PAGE Gel
ARG2 transfected lysate.
Western Blot
Lane 1: ARG2 transfected lysate ( 38.6 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — ARG2
Entrez GeneID
384GeneBank Accession#
NM_001172.3Protein Accession#
-Gene Name
ARG2
Gene Alias
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Gene Description
arginase, type II
Omim ID
107830Gene Ontology
HyperlinkGene Summary
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described. [provided by RefSeq
Other Designations
A-II|L-arginine amidinohydrolase|L-arginine ureahydrolase|kidney arginase|nonhepatic arginase
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Interactome
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Pathway
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Disease
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