TRIM23 monoclonal antibody (M05), clone 3E8
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant TRIM23.
Immunogen
TRIM23 (AAH22510, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MATLVVNKLGAGVDSGRQGSRGTAVVKVLECGVCEDVFSLQGDKVPRLLLCGHTVCHDCLTRLPLHGRAIRCPFDRQVTDLGDSGVWGLKKNFALLELLERLQNGPIGQY
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged TRIM23 is approximately 3ng/ml as a capture antibody.ELISA
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Gene Info — TRIM23
Entrez GeneID
373GeneBank Accession#
BC022510Protein Accession#
AAH22510Gene Name
TRIM23
Gene Alias
ARD1, ARFD1, RNF46
Gene Description
tripartite motif-containing 23
Omim ID
601747Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described. [provided by RefSeq
Other Designations
ADP-ribosylation factor domain protein 1|ADP-ribosylation factor domain protein 1, 64kDa|ARF domain protein 1|GTP-binding protein ARD-1|OTTHUMP00000123453|tripartite motif protein TRIM23
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