ABCC6 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human ABCC6 DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — ABCC6
Entrez GeneID
368GeneBank Accession#
NM_001079528.1Protein Accession#
NP_001072996.1Gene Name
ABCC6
Gene Alias
ABC34, ARA, EST349056, MLP1, MOATE, MRP6, PXE, PXE1
Gene Description
ATP-binding cassette, sub-family C (CFTR/MRP), member 6
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq
Other Designations
ATP-binding cassette, sub-family C, member 6|anthracycline resistance-associated
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Interactome
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Pathway
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Disease
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