ABCC6 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human ABCC6 full-length ORF ( NP_001072996.1, 1 a.a. - 99 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MAAPAEPCAGQGVWNQTEPEPAATSLLSLCFLRTAGVWVPPMYLWVLGPIYLLFIHHHGRGYLRMSPLFKAKMVAAIPGSLEPGNVRGRQGTGWNLVKS
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.2
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ABCC6
Entrez GeneID
368GeneBank Accession#
NM_001079528.1Protein Accession#
NP_001072996.1Gene Name
ABCC6
Gene Alias
ABC34, ARA, EST349056, MLP1, MOATE, MRP6, PXE, PXE1
Gene Description
ATP-binding cassette, sub-family C (CFTR/MRP), member 6
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq
Other Designations
ATP-binding cassette, sub-family C, member 6|anthracycline resistance-associated
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Interactome
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Pathway
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Disease
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