BIRC3 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
BIRC3 transfected lysate.
Western Blot
Lane 1: BIRC3 transfected lysate ( 68.40 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-BIRC3 full-length
Host
Human
Theoretical MW (kDa)
68.4
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-BIRC3 antibody (H00000330-D01P) by Western Blots.
SDS-PAGE Gel
BIRC3 transfected lysate.
Western Blot
Lane 1: BIRC3 transfected lysate ( 68.40 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — BIRC3
Entrez GeneID
330GeneBank Accession#
NM_001165Protein Accession#
NP_001156.1Gene Name
BIRC3
Gene Alias
AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49
Gene Description
baculoviral IAP repeat-containing 3
Omim ID
601721Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq
Other Designations
TNFR2-TRAF signaling complex protein|apoptosis inhibitor 2|baculoviral IAP repeat-containing protein 3|inhibitor of apoptosis protein 1|mammalian IAP homolog C
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Interactome
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Pathway
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Disease
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