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Last updated: 2016/10/23
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APBB1 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00000322-T02
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-APBB1 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 77
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-APBB1 antibody (H00000322-B01P) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00000322-T02
    APBB1 transfected lysate.
    Western Blot
    QC Testing of H00000322-T02
    Lane 1: APBB1 transfected lysate ( 77 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 322
  • Gene Name:
  • APBB1
  • Gene Alias:
  • FE65,MGC:9072,RIR
  • Gene Description:
  • amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
  • Gene Summary:
  • The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants have been described for this gene but some of their full length sequence is not known. [provided by RefSeq
  • Other Designations:
  • adaptor protein FE65a2,amyloid beta A4 precursor protein-binding, family B, member 1,stat-like protein
  • Gene Pathway
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