AOC2 (Human) IP-WB Antibody Pair
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More Files
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Immunoprecipitation of AOC2 transfected lysate using rabbit polyclonal anti-AOC2 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-AOC2.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of AOC2 transfected lysate using rabbit polyclonal anti-AOC2 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-AOC2.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-AOC2 (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-AOC2 (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — AOC2
Entrez GeneID
314Gene Name
AOC2
Gene Alias
DAO2, RAO
Gene Description
amine oxidase, copper containing 2 (retina-specific)
Omim ID
602268Gene Ontology
HyperlinkGene Summary
Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
amine oxidase, copper containing 2
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Interactome
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Pathway
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