AOC2 polyclonal antibody (A01)
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More Files
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Western Blot (Cell lysate)
AOC2 polyclonal antibody (A01), Lot # 051206JC01 Western Blot analysis of AOC2 expression in IMR-32 ( Cat # L008V1 ).
Western Blot detection against Immunogen (37.11 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant AOC2.
Immunogen
AOC2 (NP_033720, 169 a.a. ~ 268 a.a) partial recombinant protein with GST tag.
Sequence
RAEFTQMWRHLKEVELPKAPIFLSSTFNYNGSTLAAVHATPRGLRSGDRATWMALYHNISGVGLFLHPVGLELLLDHRALDPAHWTVQQVFYLGHYYADL
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.11 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
AOC2 polyclonal antibody (A01), Lot # 051206JC01 Western Blot analysis of AOC2 expression in IMR-32 ( Cat # L008V1 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — AOC2
Entrez GeneID
314GeneBank Accession#
NM_009590Protein Accession#
NP_033720Gene Name
AOC2
Gene Alias
DAO2, RAO
Gene Description
amine oxidase, copper containing 2 (retina-specific)
Omim ID
602268Gene Ontology
HyperlinkGene Summary
Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
amine oxidase, copper containing 2
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Interactome
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Pathway
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Publication Reference
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The unique substrate specificity of human AOC2, a semicarbazide-sensitive amine oxidase.
Kaitaniemi S, Elovaara H, Gron K, Kidron H, Liukkonen J, Salminen T, Salmi M, Jalkanen S, Elima K.
Cellular and Molecular Life Sciences 2009 Aug; 66(16):2743.
Application：Flow Cyt, IF, IHC-Fr, IHC-P, Human, HEK 293 cells, Human retina.
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The unique substrate specificity of human AOC2, a semicarbazide-sensitive amine oxidase.
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