ANXA6 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
ANXA6 MaxPab polyclonal antibody. Western Blot analysis of ANXA6 expression in human kidney.
Western Blot (Transfected lysate)
Western Blot analysis of ANXA6 expression in transfected 293T cell line (H00000309-T01) by ANXA6 MaxPab polyclonal antibody.
Lane 1: ANXA6 transfected lysate(74.03 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human ANXA6 protein.
Immunogen
ANXA6 (NP_001146.2, 1 a.a. ~ 673 a.a) full-length human protein.
Sequence
MAKPAQGAKYRGSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQLVAAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRSTPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSGEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEGGENLDQAREDAQVAAEILEIADTPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIVQSVKNKPLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTSGDFLKALLALCGGED
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (94); Rat (95)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
ANXA6 MaxPab polyclonal antibody. Western Blot analysis of ANXA6 expression in human kidney.Western Blot (Transfected lysate)
Western Blot analysis of ANXA6 expression in transfected 293T cell line (H00000309-T01) by ANXA6 MaxPab polyclonal antibody.
Lane 1: ANXA6 transfected lysate(74.03 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — ANXA6
Entrez GeneID
309GeneBank Accession#
NM_001155.3Protein Accession#
NP_001146.2Gene Name
ANXA6
Gene Alias
ANX6, CBP68
Gene Description
annexin A6
Omim ID
114070Gene Ontology
HyperlinkGene Summary
Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Exon 21 of annexin VI is alternatively spliced, giving rise to two isoforms that differ by a 6-amino acid insertion at the start of the seventh repeat. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis. [provided by RefSeq
Other Designations
annexin VI|annexin VI (p68)|calcium-binding protein p68|calelectrin|calphobindin II
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Interactome
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Disease
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Publication Reference
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Annexin VI is a mannose-6-phosphate-independent endocytic receptor for bovine beta-glucuronidase.
Ramirez-Mata A, Michalak C, Mendoza-Hernandez G, Leon-Del-Rio A, Gonzalez-Noriega A.
Exp Cell Res 2011 Oct; 317(16):2364.
Application：Func, Human, Human β-glucuronidase-deficient fibroblast cell line (BGH1).
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Annexin VI is a mannose-6-phosphate-independent endocytic receptor for bovine beta-glucuronidase.
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