ANXA3 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human ANXA3 full-length ORF ( AAH00871, 1 a.a. - 323 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MASIWVGHRGTVRDYPDFSPSVDAEAIQKAIRGIGTDEKMLISILTERSNAQRQLIVKEYQAAYGKELKDDLKGDLSGHFEHLMVALVTPPAVFDAKQLKKSMKGAGTNEDALIEILTTRTSRQMKDISQAYYTVYKKSLGDDISSETSGDFRKALLTLADGRRDESLKVDEHLAKQDAQILYKAGENRWGTDEDKFTEILCLRSFPQLKLTFDEYRNISQKDIVDSIKGELSGHFEDLLLAIVNCVRNTPAFLAERLHRALKGIGTDEFTLNRIMVSRSEIDLLDIRTEFKKHYGYSLYSAIKSDTSGDYEITLLKICGGDD
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
61.27
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ANXA3
Entrez GeneID
306GeneBank Accession#
BC000871Protein Accession#
AAH00871Gene Name
ANXA3
Gene Alias
ANX3
Gene Description
annexin A3
Omim ID
106490Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phopholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation. [provided by RefSeq
Other Designations
Annexin III (lipocortin III)|annexin III (lipocortin III, 1,2-cyclic-inositol-phosphate phosphodiesterase, placental anticoagulant protein III, calcimedin 35-alpha)|calcimedin 35-alpha
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Interactome
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Publication Reference
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Noninvasive Precision Screening of Prostate Cancer by Urinary Multimarker Sensor and Artificial Intelligence Analysis.
Hojun Kim, Sungwook Park, In Gab Jeong, Sang Hoon Song, Youngdo Jeong, Choung-Soo Kim, Kwan Hyi Lee.
ACS Nano 2020 Dec; 15(3):4054.
Application:Func, Human, Human urine.
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Ultrasensitive and label-free detection of annexin A3 based on quartz crystal microbalance.
Young Jun Kim Md. Mahbubur Rahman Jae-Joon Lee.
Sensors and Actuators. B, Chemical 2013 Feb; 177:172.
Application:Func, Quant, Human, As a standard, Human serum, Human urine.
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A multiplex model of combining gene-based, protein-based, and metabolite-based with positive and negative markers in urine for the early diagnosis of prostate cancer.
Cao DL, Ye DW, Zhang HL, Zhu Y, Wang YX, Yao XD.
Prostate 2011 May; 71(7):700.
Application:WB-Re, As a standard, Recombinant protein.
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Annexin A3 in Urine: A Highly Specific Noninvasive Marker for Prostate Cancer Early Detection.
Schostak M, Schwall GP, Poznanovic S, Groebe K, Muller M, Messinger D, Miller K, Krause H, Pelzer A, Horninger W, Klocker H, Hennenlotter J, Feyerabend S, Stenzl A, Schrattenholz A.
The Journal of Urology 2008 Nov; 181(1):343.
Application:Quant.
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Differential radioactive quantification of protein abundance ratios between benign and malignant prostate tissues: Cancer association of annexin A3.
Wozny W, Schroer K, Schwall GP, Poznanovic S, Stegmann W, Dietz K, Rogatsch H, Schaefer G, Huebl H, Klocker H, Schrattenholz A, Cahill MA.
Proteomics 2007 Jan; 7(2):313.
Application:WB, Recombinant protein.
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Noninvasive Precision Screening of Prostate Cancer by Urinary Multimarker Sensor and Artificial Intelligence Analysis.
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