Western blot analysis of ANXA3 over-expressed 293 cell line, cotransfected with ANXA3 Validated Chimera RNAi ( Cat # H00000306-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with ANXA3 monoclonal antibody (M12), clone 4F1 (Cat # H00000306-M12 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phopholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation. [provided by RefSeq
Annexin III (lipocortin III),annexin III (lipocortin III, 1,2-cyclic-inositol-phosphate phosphodiesterase, placental anticoagulant protein III, calcimedin 35-alpha),calcimedin 35-alpha