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BIN1 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00000274-T01
  • Visit Frequency :
  • Countries :
  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-BIN1 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 53.13
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-BIN1 antibody (H00000274-B01) by Western Blots.
    Western Blot
    QC Testing of H00000274-T01
    Lane 1: BIN1 transfected lysate ( 53 KDa)
    Lane 2: Non-transfected lysate.
    SDS-PAGE Gel
    QC Testing of H00000274-T01
    BIN1 transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 274
  • Gene Name:
  • BIN1
  • Gene Alias:
  • AMPH2,AMPHL,DKFZp547F068,MGC10367,SH3P9
  • Gene Description:
  • bridging integrator 1
  • Gene Summary:
  • This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynanim, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000162179,OTTHUMP00000162183,amphiphysin II,amphiphysin-like,box dependant MYC interacting protein 1
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