ALOX15B rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human ALOX15B peptide using ARM Technology.
Immunogen
A synthetic peptide of human ALOX15B is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human ALOX15B peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — ALOX15B
Entrez GeneID
247GeneBank Accession#
ALOX15BGene Name
ALOX15B
Gene Alias
15-LOX-2
Gene Description
arachidonate 15-lipoxygenase, type B
Omim ID
603697Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq
Other Designations
15S-lipoxygenase|OTTHUMP00000135321|arachidonate 15-lipoxygenase 2|arachidonate 15-lipoxygenase, second type|arachidonate omega(6) lipoxygenase
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