ALOX12B polyclonal antibody (A01)
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More Files
- More Functions
Western Blot (Cell lysate)
ALOX12B polyclonal antibody (A01), Lot # 051130JC01 Western Blot analysis of ALOX12B expression in Jurkat ( Cat # L017V1 ).
Western Blot detection against Immunogen (36.12 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant ALOX12B.
Immunogen
ALOX12B (NP_001130, 171 a.a. ~ 261 a.a) partial recombinant protein with GST tag.
Sequence
NPNRPEWNGYIPGFPILINFKATKFLNLNLRYSFLKTASFFVRLGPMALAFKVRGLLDCKHSWKRLKDIRKIFPGKKSVVSEYVAEHWAED
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (82); Rat (84)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.12 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
ALOX12B polyclonal antibody (A01), Lot # 051130JC01 Western Blot analysis of ALOX12B expression in Jurkat ( Cat # L017V1 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — ALOX12B
Entrez GeneID
242GeneBank Accession#
NM_001139Protein Accession#
NP_001130Gene Name
ALOX12B
Gene Alias
12R-LOX
Gene Description
arachidonate 12-lipoxygenase, 12R type
Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme involved in the converstion of arachidonic acid to 12R-hydroxyeicosatetraenoic acid. Mutations in this gene are associated with nonbullous congenital ichthyosiform erythroderma. [provided by RefSeq
Other Designations
epidermis-type lipoxygenase 12
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Interactome
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Pathway
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Disease
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Publication Reference
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A role for 12R-lipoxygenase in MUC5AC expression by respiratory epithelial cells.
Garcia-Verdugo I, BenMohamed F, Tattermusch S, Leduc D, Charpigny G, Chignard M, Ollero M, Touqui L.
The European Respiratory Journal 2012 Sep; 40(3):714.
Application：WB-Tr, Human, NCI-H292 cells.
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Hepoxilin A(3) (HXA(3)) synthase deficiency is causative of a novel ichthyosis form.
Nigam S, Zafiriou MP, Deva R, Kerstin N, Geilen C, Ciccoli R, Sczepanski M, Lohse M.
FEBS Letters 2007 Dec; 582(2):279.
Application：IF, Human, Epidermal scales from the patient and in the bioptic skin from healthy subject.
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A role for 12R-lipoxygenase in MUC5AC expression by respiratory epithelial cells.
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