ALOX5AP DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human ALOX5AP DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MDQETVGNVVLLAIVTLISVVQNGFFAHKVEHESRTQNGRSFQRTGTLAFERVYTANQNCVDAYPTFLAVLWSAGLLCSQVPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIILFLFLMSVAGIFNYYLIFFFGSDFENYIKTISTTISPLLLIP
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (92); Rat (92)
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — ALOX5AP
Entrez GeneID
241GeneBank Accession#
NM_001629.2Protein Accession#
NP_001620.2Gene Name
ALOX5AP
Gene Alias
FLAP
Gene Description
arachidonate 5-lipoxygenase-activating protein
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. [provided by RefSeq
Other Designations
MK-886-binding protein|OTTHUMP00000018204|five-lipoxygenase activating protein
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Interactome
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Disease
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