ALOX5AP rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human ALOX5AP peptide using ARM Technology.
Immunogen
A synthetic peptide of human ALOX5AP is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human ALOX5AP peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — ALOX5AP
Entrez GeneID
241GeneBank Accession#
ALOX5APGene Name
ALOX5AP
Gene Alias
FLAP
Gene Description
arachidonate 5-lipoxygenase-activating protein
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. [provided by RefSeq
Other Designations
MK-886-binding protein|OTTHUMP00000018204|five-lipoxygenase activating protein
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Interactome
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Disease
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