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Last updated: 2016/12/4
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ALOX5 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00000240-T01
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-ALOX5 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 78
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-ALOX5 antibody (H00000240-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00000240-T01
    ALOX5 transfected lysate.
    Western Blot
    QC Testing of H00000240-T01
    Lane 1: ALOX5 transfected lysate ( 78 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 240
  • Protein Accession#:
  • -
  • Gene Name:
  • ALOX5
  • Gene Alias:
  • 5-LO,5-LOX,5LPG,LOG5,MGC163204
  • Gene Description:
  • arachidonate 5-lipoxygenase
  • Gene Summary:
  • This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000019502,arachidonic acid 5-lipoxygenase,leukotriene A4 synthase
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