ALDOA monoclonal antibody (M02), clone 3C12-6D11
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More Files
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Western Blot (Cell lysate)
ALDOA monoclonal antibody (M01), clone 3C12-6D11 Western Blot analysis of ALDOA expression in A-431 ( Cat # L015V1 ).
Western Blot (Transfected lysate)
Western Blot analysis of ALDOA expression in transfected 293T cell line by ALDOA monoclonal antibody (M02), clone 3C12-6D11.
Lane 1: ALDOA transfected lysate(39 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of monoclonal antibody to ALDOA on A-431 cell. [antibody concentration 10 ug/ml]
Western Blot detection against Immunogen (65.78 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant ALDOA.
Immunogen
ALDOA (AAH10660.1, 1 a.a. ~ 364 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MPYQYPALTPEQKKELSDIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYRQLLLTADDRVNPCIGGVILFHETLYQKADDGRPFPQVIKSKGGVVGIKVDKGVVPLAGTNGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPSALAIMENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHIYLEGTLLKPNMVTPGHACTQKFSHEEIAMATVTALRRTVPPAVTGITFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAAQEEYVKRALANSLACQGKYTPSGQAGAAASESLFVSNHAY
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (98); Rat (97)
Isotype
IgG1 kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (65.78 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
ALDOA monoclonal antibody (M01), clone 3C12-6D11 Western Blot analysis of ALDOA expression in A-431 ( Cat # L015V1 ).Western Blot (Transfected lysate)
Western Blot analysis of ALDOA expression in transfected 293T cell line by ALDOA monoclonal antibody (M02), clone 3C12-6D11.
Lane 1: ALDOA transfected lysate(39 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to ALDOA on A-431 cell. [antibody concentration 10 ug/ml] -
Gene Info — ALDOA
Entrez GeneID
226GeneBank Accession#
BC010660Protein Accession#
AAH10660.1Gene Name
ALDOA
Gene Alias
ALDA, MGC10942, MGC17716, MGC17767
Gene Description
aldolase A, fructose-bisphosphate
Omim ID
103850Gene Ontology
HyperlinkGene Summary
This gene product, Aldolase A (fructose-bisphosphate aldolase) is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants which encode the same protein. [provided by RefSeq
Other Designations
aldolase A|fructose-1,6-bisphosphate triosephosphate-lyase|fructose-bisphosphate aldolase A
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Interactome
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Pathway
- Biosynthesis of alkaloids derived from histidine and purine
- Biosynthesis of alkaloids derived from ornithine
- Biosynthesis of alkaloids derived from shikimate pathway
- Biosynthesis of alkaloids derived from terpenoid and polyketide
- Biosynthesis of phenylpropanoids
- Biosynthesis of plant hormones
- Biosynthesis of terpenoids and steroids
- Carbon fixation in photosynthetic organisms
- Fructose and mannose metabolism
+ View More Disease
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Disease
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Publication Reference
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High expression of fructose-bisphosphate aldolase A induces progression of renal cell carcinoma.
Huang Z, Hua Y, Tian Y, Qin C, Qian J, Bao M, Liu Y, Wang S, Cao Q, Ju X, Wang Z, Gu M.
Oncology Reports 2018 Jun; 39(6):2996.
Application：IHC-P, WB-Ce, WB-Tr, Human, 769-P, 786-0, ACHN, Caki-1, HK-2 cells, Renal cell carcinoma, Tissue microarray.
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Grade-dependent proteomic characterization of kidney cancer.
Perroud B, Ishimaru T, Borowsky AD, Weiss RH.
Molecular & Cellular Proteomics 2009 May; 8(5):971.
Application：WB-Ti, Human, Human clear cell renal cell carcinoma.
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High expression of fructose-bisphosphate aldolase A induces progression of renal cell carcinoma.
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