NR0B1 DNAxPab
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More Files
- More Functions
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human NR0B1 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MAGENHQWQGSILYNMLMSAKQTRAAPEAPETRLVDQCWGCSCGDEPGVGREGLLGGRNVALLYRCCFCGKDHPRQGSILYSMLTSAKQTYAAPKAPEATLGPCWGCSCGSDPGVGRAGLPGGRPVALLYRCCFCGEDHPRQGSILYSLLTSSKQTHVAPAAPEARPGGAWWDRSYFAQRPGGKEALPGGRATALLYRCCFCGEDHPQQGSTLYCVPTSTNQAQAAPEERPRAPWWDTSSGALRPVALKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELAQDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQAIKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQGPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEMLCTKI
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (65)
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — NR0B1
Entrez GeneID
190GeneBank Accession#
NM_000475.3Protein Accession#
NP_000466.2Gene Name
NR0B1
Gene Alias
AHC, AHCH, AHX, DAX-1, DAX1, DSS, GTD, HHG, NROB1
Gene Description
nuclear receptor subfamily 0, group B, member 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism. [provided by RefSeq
Other Designations
OTTHUMP00000023102|gonadotropin deficiency|nuclear hormone receptor
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Interactome
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