NR0B1 monoclonal antibody (M02), clone 2F12
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More Files
- More Functions
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged NR0B1 is approximately 1ng/ml as a capture antibody.
Immunofluorescence
Immunofluorescence of monoclonal antibody to NR0B1 on HeLa cell . [antibody concentration 10 ug/ml]
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant NR0B1.
Immunogen
NR0B1 (NP_000466, 361 a.a. ~ 470 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
IKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQGPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEMLCTKI
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (76)
Isotype
IgG2a kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged NR0B1 is approximately 1ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to NR0B1 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — NR0B1
Entrez GeneID
190GeneBank Accession#
NM_000475Protein Accession#
NP_000466Gene Name
NR0B1
Gene Alias
AHC, AHCH, AHX, DAX-1, DAX1, DSS, GTD, HHG, NROB1
Gene Description
nuclear receptor subfamily 0, group B, member 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism. [provided by RefSeq
Other Designations
OTTHUMP00000023102|gonadotropin deficiency|nuclear hormone receptor
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