AGXT DNAxPab
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human AGXT DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MASHKLLVTPLKALLKPLSIPNQLLLGPGPSNLPPRIMAAGGLQMIGSMSKDMYQIMDEIKEGIQYVFQTRNPLTLVISGSGHCALEAALVNVLEPRDSFLVGANGIWGQRAVDIGERIGARVHPMTKDPGGHYTLQEVEEGLAQHKPVLLFLTHGESSTGVLQPLDGFGELCHRYKCLLLVDSVASLGGTPLYMDRQGIDILYSGSQKALNAPPGTSLISFSDKAKKKMYSRKTKPFSFYLDIKWLANFWGCDDQPRMYHHTIPVISLYSLRESLALIAEQGLENSWRQHREAAAYLHGRLQALGLQLFVKDPALRLPTVTTVAVPAGYDWRDIVSYVMDHFDIEIMGGLGPSTGKVLRIGLLGCNATRENVDRVTEALRAALQHCPKKKL
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (76); Rat (79)
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — AGXT
Entrez GeneID
189GeneBank Accession#
AK315331.1Protein Accession#
BAG37731.1Gene Name
AGXT
Gene Alias
AGT, AGT1, AGXT1, PH1, SPAT, SPT, TLH6
Gene Description
alanine-glyoxylate aminotransferase
Gene Ontology
HyperlinkGene Summary
This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. [provided by RefSeq
Other Designations
L-alanine: glyoxylate aminotransferase 1|hepatic peroxisomal alanine:glyoxylate aminotransferase|serine-pyruvate aminotransferase|serine:pyruvate aminotransferase
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Interactome
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Pathway
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Disease
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