APLNR DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human APLNR DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — APLNR
Entrez GeneID
187GeneBank Accession#
DQ890844.2Protein Accession#
ABM81770.1Gene Name
APLNR
Gene Alias
AGTRL1, APJ, APJR, FLJ90771, MGC45246
Gene Description
apelin receptor
Omim ID
600052Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified. [provided by RefSeq
Other Designations
APJ (apelin) receptor|angiotensin II receptor-like 1|angiotensin receptor-like 1
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Interactome
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Pathway
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Disease
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