AGC1 monoclonal antibody (M01), clone 2A8
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant AGC1.
Immunogen
AGC1 (NP_037359, 56 a.a. ~ 155 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
PMHPVTTAPSTAPLAPRIKWSRVSKEKEVVLLVATEGRVRVNSAYQDKVSLPNYPAIPSDATLEVQSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVF
Host
Mouse
Reactivity
Human
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged AGC1 is approximately 0.1ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to ACAN on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — ACAN
Entrez GeneID
176GeneBank Accession#
NM_013227Protein Accession#
NP_037359Gene Name
ACAN
Gene Alias
AGC1, AGCAN, CSPG1, CSPGCP, MSK16, SEDK
Gene Description
aggrecan
Gene Ontology
HyperlinkGene Summary
This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene. [provided by RefSeq
Other Designations
aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122)|aggrecan proteoglycan|cartilage-specific proteoglycan core protein|chondroitin sulfate proteoglycan 1|large aggregating proteo
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Interactome
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Disease
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