AP2A1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human AP2A1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human AP2A1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human AP2A1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — AP2A1
Entrez GeneID
160GeneBank Accession#
AP2A1Gene Name
AP2A1
Gene Alias
ADTAA, AP2-ALPHA, CLAPA1
Gene Description
adaptor-related protein complex 2, alpha 1 subunit
Omim ID
601026Gene Ontology
HyperlinkGene Summary
This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms. A third transcript variant has been described, but its full length nature has not been determined. [provided by RefSeq
Other Designations
100 kDa coated vesicle protein A|adaptin, alpha A|clathrin-associated/assembly/adaptor protein, large, alpha 1
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Interactome
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Pathway
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