ADSL 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
ADSL transfected lysate.
Western Blot
Lane 1: ADSL transfected lysate ( 53.35 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-ADSL full-length
Host
Human
Theoretical MW (kDa)
53.35
Interspecies Antigen Sequence
Mouse (94); Rat (93)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-ADSL antibody (H00000158-B01) by Western Blots.
SDS-PAGE Gel
ADSL transfected lysate.
Western Blot
Lane 1: ADSL transfected lysate ( 53.35 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — ADSL
Entrez GeneID
158GeneBank Accession#
NM_000026.1Protein Accession#
NP_000017.1Gene Name
ADSL
Gene Alias
AMPS, ASASE, ASL
Gene Description
adenylosuccinate lyase
Gene Ontology
HyperlinkGene Summary
Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000028724|adenylosuccinase
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Interactome
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Pathway
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