ADSL purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Cell lysate)
ADSL MaxPab rabbit polyclonal antibody. Western Blot analysis of ADSL expression in K-562.
Western Blot (Transfected lysate)
Western Blot analysis of ADSL expression in transfected 293T cell line (H00000158-T02) by ADSL MaxPab polyclonal antibody.
Lane 1: ADSL transfected lysate(54.90 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human ADSL protein.
Immunogen
ADSL (NP_000017.1, 1 a.a. ~ 484 a.a) full-length human protein.
Sequence
MAAGGDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKAELCL
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (94); Rat (93)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
ADSL MaxPab rabbit polyclonal antibody. Western Blot analysis of ADSL expression in K-562.Western Blot (Transfected lysate)
Western Blot analysis of ADSL expression in transfected 293T cell line (H00000158-T02) by ADSL MaxPab polyclonal antibody.
Lane 1: ADSL transfected lysate(54.90 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — ADSL
Entrez GeneID
158GeneBank Accession#
NM_000026.1Protein Accession#
NP_000017.1Gene Name
ADSL
Gene Alias
AMPS, ASASE, ASL
Gene Description
adenylosuccinate lyase
Gene Ontology
HyperlinkGene Summary
Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000028724|adenylosuccinase
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Interactome
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Pathway
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