ADK polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant ADK.
Immunogen
ADK (NP_001114, 236 a.a. ~ 345 a.a) partial recombinant protein with GST tag.
Sequence
FETKDIKEIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASIIIRRTGCTFPEKPDFH
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (90); Rat (87)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (38.21 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
ADK polyclonal antibody (A01), Lot # 051116JC01 Western Blot analysis of ADK expression in HL-60 ( Cat # L014V1 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — ADK
Entrez GeneID
132GeneBank Accession#
NM_001123Protein Accession#
NP_001114Gene Name
ADK
Gene Alias
AK
Gene Description
adenosine kinase
Omim ID
102750Gene Ontology
HyperlinkGene Summary
This gene encodes adenosine kinase, an abundant enzyme in mammalian tissues. The enzyme catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Alternative splicing results in two transcript variants encoding different isoforms. Both isoforms of the enzyme phosphorylate adenosine with identical kinetics and both require Mg2+ for activity. [provided by RefSeq
Other Designations
OTTHUMP00000019864|OTTHUMP00000019865|adenosine 5'-phosphotransferase
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Interactome
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Pathway
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Disease
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