ADH5 monoclonal antibody (M12), clone 2D11
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More Files
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Western Blot (Cell lysate)
ADH5 monoclonal antibody (M12), clone 2D11. Western Blot analysis of ADH5 expression in IMR-32.
Western Blot (Transfected lysate)
Western Blot analysis of ADH5 expression in transfected 293T cell line by ADH5 monoclonal antibody (M12), clone 2D11.
Lane 1: ADH5 transfected lysate (Predicted MW: 39.7 KDa).
Lane 2: Non-transfected lysate.
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ADH5 is 0.1 ng/ml as a capture antibody.
Western Blot detection against Immunogen (66.88 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant ADH5.
Immunogen
ADH5 (AAH14665, 1 a.a. ~ 374 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MANEVIKCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKIIATAVCHTDAYTLSGADPEGCFPVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGKGLMPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTGYGAAVNTAKLEPGSVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATECINPQDFSKPIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAASGGEIATRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAFELMHSGKSIRTVVKI
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (93); Rat (94)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (66.88 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
ADH5 monoclonal antibody (M12), clone 2D11. Western Blot analysis of ADH5 expression in IMR-32.Western Blot (Transfected lysate)
Western Blot analysis of ADH5 expression in transfected 293T cell line by ADH5 monoclonal antibody (M12), clone 2D11.
Lane 1: ADH5 transfected lysate (Predicted MW: 39.7 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ADH5 is 0.1 ng/ml as a capture antibody.ELISA
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Gene Info — ADH5
Entrez GeneID
128GeneBank Accession#
BC014665Protein Accession#
AAH14665Gene Name
ADH5
Gene Alias
ADH-3, ADHX, FDH, GSNOR
Gene Description
alcohol dehydrogenase 5 (class III), chi polypeptide
Omim ID
103710Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene. [provided by RefSeq
Other Designations
alcohol dehydrogenase (class III), chi polypeptide|class III alcohol dehydrogenase 5|formaldehyde dehydrogenase|glutathione-dependent formaldehyde dehydrogenase
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Interactome
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Pathway
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Disease
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