ADH5 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
ADH5 MaxPab rabbit polyclonal antibody. Western Blot analysis of ADH5 expression in mouse kidney.
Western Blot (Transfected lysate)
Western Blot analysis of ADH5 expression in transfected 293T cell line (H00000128-T02) by ADH5 MaxPab polyclonal antibody.
Lane 1: ADH5 transfected lysate(39.70 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to ADH5 on HeLa cell. [antibody concentration 20 ug/ml]
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human ADH5 protein.
Immunogen
ADH5 (NP_000662.3, 1 a.a. ~ 374 a.a) full-length human protein.
Sequence
MANEVIKCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKIIATAVCHTDAYTLSGADPEGCFPVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGKGLMPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTGYGAAVNTAKLEPGSVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATECINPQDFSKPIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAASGEEIATRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAFELMHSGKSIRTVVKI
Host
Rabbit
Reactivity
Human, Mouse
Interspecies Antigen Sequence
Mouse (93); Rat (94)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
ADH5 MaxPab rabbit polyclonal antibody. Western Blot analysis of ADH5 expression in mouse kidney.Western Blot (Transfected lysate)
Western Blot analysis of ADH5 expression in transfected 293T cell line (H00000128-T02) by ADH5 MaxPab polyclonal antibody.
Lane 1: ADH5 transfected lysate(39.70 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to ADH5 on HeLa cell. [antibody concentration 20 ug/ml] -
Gene Info — ADH5
Entrez GeneID
128GeneBank Accession#
NM_000671.3Protein Accession#
NP_000662.3Gene Name
ADH5
Gene Alias
ADH-3, ADHX, FDH, GSNOR
Gene Description
alcohol dehydrogenase 5 (class III), chi polypeptide
Omim ID
103710Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene. [provided by RefSeq
Other Designations
alcohol dehydrogenase (class III), chi polypeptide|class III alcohol dehydrogenase 5|formaldehyde dehydrogenase|glutathione-dependent formaldehyde dehydrogenase
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Interactome
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Pathway
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Disease
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