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ACTL6A Pre-design Chimera RNAi

  • Catalog # : H00000086-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens actin-like 6A (ACTL6A), transcript variant 1, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_004301
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 86
  • Gene Name:
  • ACTL6A
  • Gene Alias:
  • ACTL6,ARPN-BETA,Arp4,BAF53A,INO80K,MGC5382
  • Gene Description:
  • actin-like 6A
  • Gene Summary:
  • This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described. [provided by RefSeq
  • Other Designations:
  • BAF complex 53 kDa subunit,BAF53,BRG1-associated factor,INO80 complex subunit K,actin-related protein 4,hArpN beta
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