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Last updated: 2016/12/4
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ACO1 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00000048-T01
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-ACO1 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 97.9
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-ACO1 antibody (H00000048-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00000048-T01
    ACO1 transfected lysate.
    Western Blot
    QC Testing of H00000048-T01
    Lane 1: ACO1 transfected lysate ( 97.9 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 48
  • Gene Name:
  • ACO1
  • Gene Alias:
  • ACONS,IREB1,IREBP,IREBP1,IRP1
  • Gene Description:
  • aconitase 1, soluble
  • Gene Summary:
  • Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs). IREs are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA. Thus, IREB1 plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000021176,OTTHUMP00000021177,OTTHUMP00000045233,aconitase 1,aconitate hydratase,citrate hydro-lyase,ferritin repressor protein,iron regulatory protein 1,iron-responsive element binding protein 1
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