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Last updated: 2017/3/26

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ACLY Pre-design Chimera RNAi

  • Catalog # : H00000047-R03
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  • Specification
  • Product Description:
  • Homo sapiens ATP citrate lyase (ACLY), transcript variants, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_001096.2,NM_001303274.1,NM_001303275.1,NM_19883
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 47
  • Gene Name:
  • ACLY
  • Gene Alias:
  • ACL,ATPCL,CLATP
  • Gene Description:
  • ATP citrate lyase
  • Gene Summary:
  • ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000164773
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