ACCN1 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human ACCN1 DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — ACCN1
Entrez GeneID
40GeneBank Accession#
NM_001094.4Protein Accession#
NP_001085.2Gene Name
ACCN1
Gene Alias
ACCN, ASIC2, ASIC2a, BNC1, BNaC1, MDEG, hBNaC1
Gene Description
amiloride-sensitive cation channel 1, neuronal
Omim ID
601784Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and ACCN3 (variant 1) has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified. [provided by RefSeq
Other Designations
degenerin|neuronal amiloride-sensitive cation channel 1
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Interactome
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Pathway
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Disease
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