ACADM (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human ACADM partial ORF ( NP_000007, 1 a.a. - 100 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MAAGFGRCCRVLRSISRFHWRSQHTKANRQREPGLGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (87); Rat (86)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ACADM
Entrez GeneID
34GeneBank Accession#
NM_000016Protein Accession#
NP_000007Gene Name
ACADM
Gene Alias
ACAD1, FLJ18227, FLJ93013, FLJ99884, MCAD, MCADH
Gene Description
acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain
Gene Ontology
HyperlinkGene Summary
This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000011345|medium-chain specific acyl-CoA dehydrogenase
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Interactome
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Pathway
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Disease
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