ABO monoclonal antibody (M08), clone 1B7
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant ABO.
Immunogen
ABO (NP_065202.2, 273 a.a. ~ 354 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
SVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVPKNHQAVRNP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (78)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (34.76 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
ABO monoclonal antibody (M08), clone 1B7. Western Blot analysis of ABO expression in A-431.Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ABO is 0.3 ng/ml as a capture antibody.ELISA
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Gene Info — ABO
Entrez GeneID
28GeneBank Accession#
NM_020469Protein Accession#
NP_065202.2Gene Name
ABO
Gene Alias
A3GALNT, A3GALT1, GTB, NAGAT
Gene Description
ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
Omim ID
110300Gene Ontology
HyperlinkGene Summary
This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The 'O' blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen. Other minor alleles have been found for this gene. [provided by RefSeq
Other Designations
ABO glycocyltransferase|ABO glycosyltransferase|B(A) alpha-1,3-galactosyltransferase|alpha 1-3-N-acetylgalactosaminyltransferase|histo-blood group A2 transferase|histo-blood group ABO protein
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Interactome
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Pathway
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Disease
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