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Last updated: 2017/8/13
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ABAT 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00000018-T02
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-ABAT full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 56.4
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-ABAT antibody (H00000018-D01P) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00000018-T02
    ABAT transfected lysate.
    Western Blot
    QC Testing of H00000018-T02
    Lane 1: ABAT transfected lysate ( 56.40 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 18
  • Gene Name:
  • ABAT
  • Gene Alias:
  • FLJ17813,GABA-AT,GABAT,NPD009
  • Gene Description:
  • 4-aminobutyrate aminotransferase
  • Gene Summary:
  • 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq
  • Other Designations:
  • GABA aminotransferase,GABA transferase,gamma-amino-N-butyrate transaminase
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