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Last updated: 2017/6/18
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ABAT (Human) Recombinant Protein (P01)

  • Catalog # : H00000018-P01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Human ABAT full-length ORF ( AAH08990, 1 a.a. - 116 a.a.) recombinant protein with GST-tag at N-terminal.
  • Sequence:
  • MENHHSPKGQRRFQRKGVIGAVFCRMSQSSPSRQGKEGCCREGTAYAKAYQFMASHLSLGKPVSTGSIPRFNKALFNKQAKCKPNHYSFIGLSMLSPENFSIGCKYSVWFSETKGF
  • Host:
  • Wheat Germ (in vitro)
  • Theoretical MW (kDa):
  • 38.5
  • Purification:
  • Glutathione Sepharose 4 Fast Flow
  • Quality Control Testing:
  • 12.5% SDS-PAGE Stained with Coomassie Blue.

    QC Testing of H00000018-P01
  • Storage Buffer:
  • 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Best use within three months from the date of receipt of this protein.
  • Applications
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Application Image
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Gene Information
  • Entrez GeneID:
  • 18
  • Gene Name:
  • ABAT
  • Gene Alias:
  • FLJ17813,GABA-AT,GABAT,NPD009
  • Gene Description:
  • 4-aminobutyrate aminotransferase
  • Gene Summary:
  • 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq
  • Other Designations:
  • GABA aminotransferase,GABA transferase,gamma-amino-N-butyrate transaminase
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