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HEY1/NCOA2 DY Translocation FISH Probe

  • Catalog # : FT0005
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Labeled FISH probes for identification of gene translocation using Fluorescent In Situ Hybridization Technique. (Technology)
  • Quality Control Testing:
  • Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.

    QC Testing of FT0005
  • Supplied Product:
  • DAPI Counterstain (1500 ng/mL ) 250 uL
  • Storage Instruction:
  • Store at 4°C in the dark.
  • Note:
  • Hybridization position of the probes on the chromosome:

  • Probe 1:
        Size:
        Fluorophore:
        Location:
  • NCOA2
    Approximately 1300kb
    Texas Red
    8q13.3
  • Probe 2:
        Size:
        Fluorophore:
        Location:
  • HEY1
    Approximately 1250kb
    FITC
    8q21.13
  • Probe Gap:
  • The gap between two probes is approximately 8,200 kb.
  • Origin:
  • Human
  • Source:
  • Genomic DNA
  • Notice:
  • We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections) enlargeenlarge this image
  • Huma lung, adenosquamous cell carcinoma (FFPE) stained with HEY1/NCOA2 DY Translocation FISH Probe. Human lung cancer showed no HEY/NCOA2 DY Translocation.
  • PDF DownloadProtocol Download
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections) enlargeenlarge this image
  • Human hemangiopericytoma (FFPE) stained with HEY1/NCOA2 DY Translocation FISH Probe. Human hemangiopericytoma showed no HEY1/NCOA2 DY translocation.
  • PDF DownloadProtocol Download
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections) enlargeenlarge this image
  • Human mesenchymal chondrosarcoma (FFPE) stained with HEY1/NCOA2 DY Translocation FISH Probe. Human mesenchymal chondrosarcoma showed no HEY1/NCOA2 DY translocation.
  • PDF DownloadProtocol Download
  • Application Image
  • Fluorescent In Situ Hybridization (Cell)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Gene Name:
  • NCOA2
  • Gene Alias:
  • GRIP1,KAT13C,MGC138808,NCoA-2,TIF2,bHLHe75
  • Gene Description:
  • nuclear receptor coactivator 2
  • Other Designations:
  • glucocorticoid receptor-interacting protein-1
  • Gene Information
  • Gene Name:
  • HEY1
  • Gene Alias:
  • BHLHb31,CHF2,HERP2,HESR1,HRT-1,MGC1274,OAF1
  • Gene Description:
  • hairy/enhancer-of-split related with YRPW motif 1
  • Gene Summary:
  • This gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq
  • Other Designations:
  • HES-related repressor protein 2,basic helix-loop-helix protein OAF1,cardiovascular helix-loop-helix factor 2,hairy-related transcription factor 1
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