KDM2B Split FISH Probe
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Specification
Product Description
Labeled FISH probes for identification of gene split using Fluorescent In Situ Hybridization Technique. (Technology).
Probe 1
Name: KDM2B
Size: Approximately 440kb
Fluorophore: Texas Red
Location: 12q24.31Probe 2
Name: KDM2B
Size: Approximately 500kb
Fluorophore: FITC
Location: 12q24.31Origin
Human
Source
Genomic DNA
Reactivity
Human
Notice
We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
Regulatory Status
For research use only (RUO)
Quality Control Testing
Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
Storage Instruction
Store at 4°C in the dark.
Note
Hybridization position of the probes on the chromosome.
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Applications
Fluorescent In Situ Hybridization (Cell)
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Gene Info — FBXL10
Entrez GeneID
84678Gene Name
FBXL10
Gene Alias
CXXC2, Fbl10, JHDM1B, KDM2B, PCCX2
Gene Description
F-box and leucine-rich repeat protein 10
Omim ID
609078Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq
Other Designations
JEMMA (Jumonji domain, EMSY-interactor, methyltransferase motif) protein|jumonji C domain-containing histone demethylase 1B|protein containing CXXC domain 2
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Interactome
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Disease
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