PHF1 Split FISH Probe
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More Files
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Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
human prostate cancer (FFPE) stained with PHF1 Split FISH Probe . human prostate cancer showed PHF1 Split.
Hybridization position of the probes on the chromosome:
Hybridization position of the probes on the chromosome:
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Specification
Product Description
Labeled FISH probes for identification of gene split using Fluorescent In Situ Hybridization Technique. (Technology).
Probe 1
Name: PHF1
Size: Approximately 380kb
Fluorophore: Tex Red
Location: 6p21.3Probe 2
Name: PHF1
Size: Approximately 930kb
Fluorophore: FITC
Location: 6p21.3Probe Gap
The gap between two probes is approximately 50 kb.
Origin
Human
Source
Genomic DNA
Reactivity
Human
Form
Liquid
Notice
We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
Regulation Status
For research use only (RUO)
Quality Control Testing
Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
Supplied Product
DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe
Storage Instruction
Store at 4°C in the dark.
Note
Hybridization position of the probes on the chromosome:
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Applications
Fluorescent In Situ Hybridization (Cell)
Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
human prostate cancer (FFPE) stained with PHF1 Split FISH Probe . human prostate cancer showed PHF1 Split. -
Gene Info — PHF1
Entrez GeneID
5252Gene Name
PHF1
Gene Alias
MTF2L2, PCL1, PHF2
Gene Description
PHD finger protein 1
Omim ID
602881Gene Ontology
HyperlinkGene Summary
This gene encodes a Polycomb group protein. The protein is a component of a histone H3 lysine-27 (H3K27)-specific methyltransferase complex, and functions in transcriptional repression of homeotic genes. The protein is also recruited to double-strand breaks, and reduced protein levels results in X-ray sensitivity and increased homologous recombination. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000029139|OTTHUMP00000029140
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Interactome
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Disease
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