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NR4A3 Split FISH Probe

  • Catalog # : FS0023
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Labeled FISH probes for identification of gene split using Fluoresecent In Situ Hybridization Technique. (Technology)
  • Quality Control Testing:
  • Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.

    QC Testing of FS0023
  • Supplied Product:
  • DAPI Counterstain (1500 ng/mL ) 250 uL
  • Storage Instruction:
  • Store at 4°C in the dark.
  • Note:
  • Hybridization position of the probes on the chromosome:

  • Probe 1:
        Size:
        Fluorophore:
        Location:
  • NR4A3(Texas Red)
    Approximately 450kb
    Texas Red
    9q31.1
  • Probe 2:
        Size:
        Fluorophore:
        Location:
  • NR4A3(FITC)
    Approximately 720kb
    FITC
    9q22.3
  • Probe Gap:
  • The gap between two probes is approximately 35 kb.
  • Origin:
  • Human
  • Source:
  • Genomic DNA
  • Notice:
  • We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections) enlargeenlarge this image
  • Human colon adenocarcinoma (FFPE) stained with NR4A3 Split FISH Probe. Human colon adenocarcinoma showed no NR4A3 gene split.
  • PDF DownloadProtocol Download
  • Application Image
  • Fluorescent In Situ Hybridization (Cell)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 8013
  • Gene Name:
  • NR4A3
  • Gene Alias:
  • CHN,CSMF,MINOR,NOR1,TEC
  • Gene Description:
  • nuclear receptor subfamily 4, group A, member 3
  • Gene Summary:
  • This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcriptional activator. The protein can efficiently bind the NGFI-B Response Element (NBRE). Three different versions of extraskeletal myxoid chondrosarcomas (EMCs) are the result of reciprocal translocations between this gene and other genes. The translocation breakpoints are associated with Nuclear Receptor Subfamily 4, Group A, Member 3 (on chromosome 9) and either Ewing Sarcome Breakpoint Region 1 (on chromosome 22), RNA Polymerase II, TATA Box-Binding Protein-Associated Factor, 68-KD (on chromosome 17), or Transcription factor 12 (on chromosome 15). Four transcript variants encoding three distinct isoforms have been identified for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000022775,OTTHUMP00000022776,chondrosarcoma, extraskeletal myxoid, fused to EWS,mitogen induced nuclear orphan receptor,neuron derived orphan receptor,translocated in extraskeletal chondrosarcoma
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