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ROS1 Split FISH Probe

  • Catalog # : FS0022
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Labeled FISH probes for identification of gene split using Fluoresecent In Situ Hybridization Technique. (Technology)
  • Quality Control Testing:
  • Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.

    QC Testing of FS0022
  • Supplied Product:
  • DAPI Counterstain (1500 ng/mL ) 250 uL
  • Storage Instruction:
  • Store at 4°C in the dark.
  • Note:
  • Hybridization position of the probes on the chromosome:

  • Probe 1:
        Size:
        Fluorophore:
        Location:
  • ROS1(TexRed)
    Approximately 310kb
    Texas Red
    6q22.1
  • Probe 2:
        Size:
        Fluorophore:
        Location:
  • ROS1(FITC)
    Approximately 670kb
    FITC
    6q22.1
  • Probe Gap:
  • The length of overlap between two probes is approximately 20 kb.
  • Origin:
  • Human
  • Source:
  • Genomic DNA
  • Notice:
  • We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections) enlargeenlarge this image
  • Human lung squamous cell carcinoma (FFPE) stained with ROS1 Split FISH Probe. Human lung squamous cell carcinoma showed ROS1 gene split.
  • PDF DownloadProtocol Download
  • Application Image
  • Fluorescent In Situ Hybridization (Cell)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 6098
  • Gene Name:
  • ROS1
  • Gene Alias:
  • MCF3,ROS,c-ros-1
  • Gene Description:
  • c-ros oncogene 1 , receptor tyrosine kinase
  • Gene Summary:
  • This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000017814,OTTHUMP00000040389,proto-oncogene c-ros-1 protein,proto-oncogene tyrosine-protein kinase ROS,transmembrane tyrosine-specific protein kinase,v-ros UR2 sarcoma virus oncogene homolog 1,v-ros avian UR2 sarcoma virus oncogene homolog 1
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