ERG Split FISH Probe
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Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
Human prostate cancer (FFPE) stained with ERG Split FISH Probe. Human prostate cancer showed ERG gene split.
Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
Human lung, adenosquamous cell carcinoma (FFPE) stained with ERG Split FISH Probe. Human lung, adenosquamous cell carcinoma showed no ERG gene split.
Hybridization position of the probes on the chromosome.
Hybridization position of the probes on the chromosome.
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Specification
Product Description
Labeled FISH probes for identification of gene split using Fluorescent In Situ Hybridization Technique. (Technology).
Probe 1
Name: ERG(Texas Red)
Size: Approximately 330kb
Fluorophore: Texas Red
Location: 21q22.2-22.3Probe 2
Name: ERG(FITC)
Size: Approximately 540kb
Fluorophore: FITC
Location: 21q22.2-22.3Probe Gap
The gap between two probes is approximately 70 kb.
Origin
Human
Source
Genomic DNA
Reactivity
Human
Form
Liquid
Notice
We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
Regulation Status
For research use only (RUO)
Quality Control Testing
Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
Supplied Product
DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe
Storage Instruction
Store at 4°C in the dark.
Note
Hybridization position of the probes on the chromosome. -
Applications
Fluorescent In Situ Hybridization (Cell)
Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
Human prostate cancer (FFPE) stained with ERG Split FISH Probe. Human prostate cancer showed ERG gene split.Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
Human lung, adenosquamous cell carcinoma (FFPE) stained with ERG Split FISH Probe. Human lung, adenosquamous cell carcinoma showed no ERG gene split. -
Gene Info — ERG
Entrez GeneID
2078Gene Name
ERG
Gene Alias
erg-3, p55
Gene Description
v-ets erythroblastosis virus E26 oncogene homolog (avian)
Omim ID
165080Gene Ontology
HyperlinkOther Designations
OTTHUMP00000115970|TMPRSS2-ERG prostate cancer specific|transcriptional regulator ERG (transforming protein ERG)|v-ets avian erythroblastosis virus E26 oncogene related|v-ets erythroblastosis virus E26 oncogene like
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Interactome
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Disease
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