SYT Split FISH Probe
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Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
Human lung, adenosquamous cell carcinoma (FFPE) stained with SYT Split FISH Probe. Human lung, adenosquamous cell carcinoma showed no SYT gene split.
Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
Human sarcoma (FFPE) stained with SYT Split FISH Probe. Left: Human sarcoma showed no SYT gene split. Right: Human sarcoma showed SYT gene split.
Hybridization position of the probes on the chromosome.
Hybridization position of the probes on the chromosome.
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Specification
Product Description
Labeled FISH probes for identification of gene split using Fluorescent In Situ Hybridization Technique. (Technology).
Probe 1
Name: SYT(FITC)
Size: Approximately 700kb
Fluorophore: FITC
Location: 18q11.2Probe 2
Name: SYT(Texas Red)
Size: Approximately 500kb
Fluorophore: Texas Red
Location: 18q11.2Probe Gap
The gap between two probes is approximately 110 kb.
Origin
Human
Source
Genomic DNA
Reactivity
Human
Form
Liquid
Notice
We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
Regulation Status
For research use only (RUO)
Quality Control Testing
Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
Supplied Product
DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe
Storage Instruction
Store at 4°C in the dark.
Note
Hybridization position of the probes on the chromosome. -
Applications
Fluorescent In Situ Hybridization (Cell)
Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
Human lung, adenosquamous cell carcinoma (FFPE) stained with SYT Split FISH Probe. Human lung, adenosquamous cell carcinoma showed no SYT gene split.Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
Human sarcoma (FFPE) stained with SYT Split FISH Probe. Left: Human sarcoma showed no SYT gene split. Right: Human sarcoma showed SYT gene split. -
Gene Info — SS18
Entrez GeneID
6760Gene Name
SS18
Gene Alias
MGC116875, SSXT, SYT, SYT-SSX1, SYT-SSX2
Gene Description
synovial sarcoma translocation, chromosome 18
Omim ID
600192Gene Ontology
HyperlinkGene Summary
O
Other Designations
SSXT/SSX4v fusion|SYT/SSX4v fusion protein|synovial sarcoma, translocated to X chromosome
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Interactome
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Publication Reference
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Detection of SYT and EWS gene rearrangements by dual-color break-apart CISH in liquid-based cytology samples of synovial sarcoma and Ewing sarcoma/primitive neuroectodermal tumor.
Kumagai A, Motoi T, Tsuji K, Imamura T, Fukusato T.
American Journal of Clinical Pathology 2010 Aug; 134(2):323.
Application：FISH, Human, Human synovial sarcoma.
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Diagnostic utility of dual-color break-apart chromogenic in situ hybridization for the detection of rearranged SS18 in formalin-fixed, paraffin-embedded synovial sarcoma.
Motoi T, Kumagai A, Tsuji K, Imamura T, Fukusato T.
Human Pathology 2010 Oct; 41(10):1397.
Application：FISH-P, Human, Human synovial sarcoma.
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Detection of SYT and EWS gene rearrangements by dual-color break-apart CISH in liquid-based cytology samples of synovial sarcoma and Ewing sarcoma/primitive neuroectodermal tumor.
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