Product Browser

Last updated: 2017/9/17

Product Compare

Product Compare Cancel Click this icon to add products to compare list. Select up to 10 products.

Quick Order (Tutorial)

Input Catalog #,
place order here!
Catalog # :
  • Where to buy
  • Choose your location

mutaFISH™ EGFR L858R L858wt Ex19wt RNA Probes

  • Catalog # : FP0002
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • mutaFISH™ EGFR L858R L858wt Ex19wt RNA Probes is designed to detect human EGFR L858R gene mutation and EGFR exon 19 deletion on single strand RNA in cells using in situ rolling-circle amplication technology.
  • Supplied Product:
  • Content:

    1. RT EGFR L858 Primer

    2. RT EGFR Ex19 Primer

    3. mutaFISH™ EGFR L858R RNA Probe

    4. mutaFISH™ EGFR L858wt RNA Probe

    5. mutaFISH™ EGFR Ex19wt RNA Probe

    6. Detection Probe-Cy3

    7. Detection Probe-Cy5

    8. Detection Probe-Texas Red
  • Storage Instruction:
  • Store at -20°C.
  • Note:
  • We recommend mutaFISH™ RNA Accessory Kit (Catalog #: KA4915) which provides necessary reagents and enzymesfor in situ reverse transcription, RNA digestion, mutaFISH™ hybridization, ligation and amplication prior to mutaFISH™.
  • Fluorophore:
  • Cy3 (Excitation wavelength: 548; Emission wavelength: 561)

    Cy5 (Excitation wavelength: 647; Emission wavelength: 665)

    Texas Red (Excitation wavelength: 595; Emission wavelength: 613)
  • Probe Position:
  • Regulatory Status:
  • For research use only (RUO)
  • Applications
  • mutation specific, Fluorescence In Situ Hybridization
  • mutation specific, Fluorescence <em>In Situ</em> Hybridization
  • The figure represents an example workflow of detecting a point mutation on single strand RNA using mutaFISH™ probes with mutaFISH™ RNA Accessory Kit.
  • Application Image
  • mutation specific, Fluorescence In Situ Hybridization
  • mutation specific, Fluorescence <em>In Situ</em> Hybridization
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 1956
  • Gene Name:
  • EGFR
  • Gene Alias:
  • ERBB,ERBB1,HER1,PIG61,mENA
  • Gene Description:
  • epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
  • Gene Summary:
  • The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq
  • Other Designations:
  • avian erythroblastic leukemia viral (v-erb-b) oncogene homolog,cell growth inhibiting protein 40,cell proliferation-inducing protein 61,epidermal growth factor receptor
  • Interactome
  • Interactome
  • Related Disease
  • RSS
  • YouTube
  • Linkedin
  • Facebook