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Last updated: 2017/10/22

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DPYD/CEN1p FISH Probe

  • Catalog # : FG0219
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Labeled FISH probes for identification of gene amplification using Fluoresecent In Situ Hybridization Technique. (Technology)
  • Quality Control Testing:
  • Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.

    QC Testing of FG0219
  • Supplied Product:
  • DAPI Counterstain (1500 ng/mL ) 250 uL
  • Storage Instruction:
  • Store at 4°C in the dark.
  • Note:
  • Hybridization position of the probes on the chromosome.

  • Probe 1:
        Size:
        Fluorophore:
        Location:
  • DPYD
    Approximately 800kb
    TexRed
    1p22
  • Probe 2:
        Size:
        Fluorophore:
        Location:
  • CEN1p
    Approximately 780kb
    FITC
    1p13.3
  • Origin:
  • Human
  • Source:
  • Genomic DNA
  • Notice:
  • We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Application Image
  • Fluorescent In Situ Hybridization (Cell)
  • Gene Information
  • Entrez GeneID:
  • 1806
  • Gene Name:
  • DPYD
  • Gene Alias:
  • DHP,DHPDHASE,DPD,MGC132008,MGC70799
  • Gene Description:
  • dihydropyrimidine dehydrogenase
  • Gene Summary:
  • The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000037640,OTTHUMP00000058954,dihydrothymine dehydrogenase,dihydrouracil dehydrogenase
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